A promising pipeline of diverse molecular structures

Pipeline

QBiotics has identified significant unmet medical needs and market opportunities in a range of therapeutic areas.

Our current focus is on treating solid tumours and chronic wounds, with an additional early programme in antibiotics.

Our anticancer drug candidate, tigilanol tiglate, is an intratumoural, oncolytic small molecule with potential in the treatment of a wide range of solid tumours by intratumoural injection. Tigilanol tiglate is currently in clinical Phase II development for the treatment of soft tissue sarcomas within a clinical trial in the United States. The development programme has been awarded Orphan Drug Designation by the FDA for this indication. Additionally, a clinical trial in head and neck cancers is underway in both the United Kindom and Australia.

Our wound healing drug candidate, EBC-1013, is a topically applied, semi-synthetic small molecule, that has the potential for the treatment of a wide range of chronic and acute wounds and burns. EBC-1013 is currently enrolling patients in its clinical Phase I safety trial in patients with venous leg ulcers in Australia.

Underpinning QBiotics' current programmes is the Company's epoxytiglianes platform. Tigilanol tiglate and EBC-1013 are two of three interlinked programmes from this platform, with an antibiotic programme in lead selection stage.

Human
Area
Molecule
Species
Indication
Trial registration #
Stage of Development
Preclinical
Phase I
Phase II
Phase IIb/III
Registration /
Marketing
Area:Oncology
Molecule:Tigilanol tiglate
Species:Human
Indication:Soft Tissue Sarcoma
Trial registration #NCT05755113
FDA Orphan Drug Designation
% Stage of development
Species:Human
Indication:Head & Neck Cancer
Trial registration #NCT05608876
% Stage of development
Area:Wounds
Molecule:EBC-1013
Species:Human
Indication:Venous Leg Ulcers
Trial registration #ACTRN12624000544572p
% Stage of development
Discovery
Area
Target
Collection
Lead optimisation
Initial
preclinical
Area:Antibiotics
Target:Multiple resistant organisms
% Stage of development

Discover our portfolio

Oncology

Tigilanol tiglate is an intratumoural oncolytic small molecule with potential to treat a wide range of solid tumours.

Wound Healing

EBC-1013 is our small molecule that has the potential for the treatment of a wide range of chronic and acute wounds and burns.

Preclinical

Our antibiotic discovery programme targets bacterial virulence.

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